Though heart disease is a major cause of disability and death, very little is understood about its genetic underpinnings. Recently, an international team of researchers at the Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Sanford-Burnham Medical Research Institute (Sanford-Burnham) and other organizations shed new light on the subject. Studying Drosophila (fruit flies), the team investigated 7061 genes and built a detailed map that shows how a portion of these genes contribute to heart function and disease. Importantly, the scientists identified a number of genes that had not previously been linked to heart disease. The research is being published as the cover story in the April 2 issue of Cell.......